Posts Tagged ‘cancer’
Introduction:-
Prostate is a glandular organ gift solely in males. It surrounds the neck of bladder & the primary half of urethra and condributes a secretion to the semen. The gland is conical in shape and measures three cm in vertical diameter and four cm in transverse diameter.It has got five lobes anterior,posterior,2 lateral and a median lobe.Since the primary part of the urethra experience it any lesion within the prostate will turn out problem in passing urine.
Diseases of the prostate gland:-
1) Prostatitis:-
This is often the inflamation of the prostate gland thanks to bacterial infection.
a pair of) Benign enlargement of the prostate:-
This is often a non cancerous tumour of the prostate seen once the age of 50. 3,Cancer of the prostate:-This is the fourth most typical explanation for death from malignant diseases in males.
Cancer of the prostate.
Cancer of the prostate is directly linked with the male sex hormones(androgens).If the amount of sex hormone will increase the growth rate of cancer also increases.It is found that when the removel of testes there’s marked reduction in the scale of tumour.
Web site of tumour:-
Prostate cancer is seen mainly in the posterior lobe.Non cancerous enlargement is seen in other lobes.
Changes in the gland in cancer:-
The gland becomes laborious with irregular surface with loss of normal lobulation .Histologically prostate cancer is an adeno carcinoma(cancer of the epithelial cells within the gland)
Growth :-
Growth rate is terribly quick in prostate cancer .The tumour compresses the urethra and produce difficulty in urination.
Unfold of tumour:-
Metastasis in cancer of prostate is terribly early.
1) Native spread:-
From the posterior lobe the cancer cells head to the lateral lobes and seminal vesicles.Tumour cells additionally move to the neck and base of the urinary bladder.
two) Lymphatic unfold:-
Through the lymph vessels cancer cells reach the inner and external illiac cluster of lymph nodes.From there cells move to retroperitonial(Behind the peritonium) and mediastinal lymph nodes(in the chest)
three) Unfold through the blood:-
Unfold of cancer cells takeplace through the periprostatic venous plexus and reaches the vertebral veins while coughing and sneezing and at last enders the vertebral bodies of the lumbar vertebrae.
Signs and symptoms of prostate cancer:–
Signs and symptoms depend upon the stage of the cancer. The subsequent symptoms could be seen.
1) No symptoms:-
Tumour is small and solely within the posterior lobe. This is often diagnosed accidentely.
a pair of) Slight issue in urination:-
Here the tumour is enlarged and urethra is slightly compressed.Shortly there will be frequent urge for urination with troublesome urination.
three) When the tumour spread to any or all nearby areas as well as neck of bladder and urethra there can be painful urination with bleeding.Urine comes drop by drop.
four) Retention of urine:-
When the urethra is totally compressed there will be retention of urine.This could lead to hydronephrosis, renal failure ect.During this condition patient may get convulsions thanks to renal failure and at last coma.
five) Signs of metastasis:-
Some patients come back with the signs and symptoms of metastasis.
a) Lumbo sacral pain because of spread of cancer cells to lumbar and sacral vertebrae.
b) Fracture of spine thanks to cancerous growth within the spine.
c) Swelling, pain and fluid assortment in the abdomen because of lesion within the abdomen.
d) Respiratory complaints due to cancer of mediastinal lymphnodes and lungs.
e) General weakness thanks to unfold of cancer to totally different elements of the body.
f) Anaemia due to involment of bone marrow and increased destruction of RBCs.
Clinical examination :-
Includes per rectal examination to feel the prostate gland,palpation of abdomen to feel the swelling in kidneys and any tumours.Patient is examined from head to foot to search out out any lesions.
Investigations:-
1) Complete blood investigations;-
RBC,WBC,Platlets,ESR,bleeding time ,clotting time ect.
a pair of) Urine analysis:-
Microscopic examination to detect pus cells,occult blood,casts,Crystals ect.
3) Renal function tests:-
Blood urea level,serum creatinine level,electrolyte level ect.
four) Serum acid phosphatase:-
Increased in cancer of prostate.
5) x-ray of the spine:-
To detect any tumour or fracture.
6) Ultra sonography;-
Provides plan regarding prostate,bladder,kidney ect.
7) C T scan:-
More detailed data regarding organs and tumour.
MRI of the spine:-
Offers detailed info about spine ,disc and nearby soft tissues.
9) Lymphangiography:-
Gives idea regarding lymphatic spread of cancer.
ten) Biopsy to confirm cancer:-
Biopsy is taken from the tumour and is send for histopathological examination below the microscope.This will detect the presence of cancer cells.
Treatment:-
one) If there is retention of urine catheterisation is needed.
2) Dialysis if kidney failure.
three) If there’s coma monitoring of all important functions along with parentral nutrition and electolyte supply.
4) Specific treatment is prostatectomy(removal of prostate)
Partial prostatectomy :-
Here only the affected lobe is removed.
Radical prostatectomy :-
Total removal of prostate along with nearby lymphnodes.
5, Hormone therapy :-
Stilbestrol is given to reduce tumour growth.Since this treatement increases the prospect for cardiovascular disease phosphorylated diethyle stilbesterol is used nowadays.
half-dozen) Chemotherapy:-Medication like cyclophosphamide, cisoplatim ect are given.
seven) Radiotherapy is also done for a few cases.
eight) Homoeopathy:-
Homoeopathic medicine like carcinocin, conium, sabal, crotalus, thuja, iodum, selinium, staphysagria, sulphur ect will be given per symptoms.Constitutional homoeopathic drugs will provide great relief and can increase the life span.
9) Yoga and meditation is additionally healpful.
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